DDA1 Antibody
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中文名稱：DDA1兔多克隆抗體
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貨號：CSB-PA880116LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat liver tissue, Mouse liver tissue
All lanes: DDA1 antibody at 2.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 12 kDa
Observed band size: 12 kDa -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA880116LA01HU at dilution of 1:100 -
Immunofluorescent analysis of PC-3 cells using CSB-PA880116LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) DDA1 Polyclonal antibody
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Uniprot No.：
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基因名：DDA1
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別名：C19orf58 antibody; Cross immune reaction antigen PCIA1 antibody; DDA1 antibody; DDA1_HUMAN antibody; DET1 and DDB1 associated 1 antibody; DET1 and DDB1 associated protein 1 antibody; DET1- and DDB1-associated protein 1 antibody; MGC2594 antibody; PCIA-1 antibody; PCIA1 antibody; Placenta cross immune reaction antigen 1 antibody; Placenta cross-immune reaction antigen 1 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human DET1- and DDB1-associated protein 1 protein (1-102AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，DDA1 Antibody (CSB-PA880116LA01HU)，的標記方式是Non-conjugated。對于DDA1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.
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基因功能參考文獻：
- surveyed the spectrum of G protein coupling of dDA1 and Damb, and we confirmed that both receptors can couple to Gs to stimulate cAMP synthesis PMID: 29166600
- The results indicate that DDA1 promotes lung cancer progression, potentially through promoting cyclins and cell cycle progression. PMID: 28211159
- Data indicate that DET1- and DDB1-associated protein 1 (DDA1)-mediated tumor progression is associated with the activation of the NF-kappa B (NFkappaB)/COP9 signalosome 2(CSN2)/glycogen synthase kinase3beta (GSK3beta) pathway. PMID: 26942699
- the c-Abl non-receptor kinase phosphorylates DDB1 at residue Tyr-316 to recruit a small regulatory protein, DDA1, leading to increased substrate ubiquitination PMID: 28087699
- PCIA1 gene expression correlates with tumor formation, invasion and metastasis PMID: 17557237
- Cells depleted of Dda1 spontaneously accumulated double-stranded DNA breaks in a similar way to Cul4A-, Cul4B- or Wdr23-depleted cells, indicating that Dda1 interacts physically and functionally with cullin-RING E3 ligases complexes. PMID: 19295130
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蛋白家族：DDA1 family
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數據庫鏈接：
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