DAPP1 Antibody
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中文名稱：DAPP1兔多克隆抗體
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貨號：CSB-PA000972
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規格：￥1090
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圖片：
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Western Blot analysis of 293 cells using BAM32 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：B cell adapter molecule of 32 kDa antibody; B lymphocyte adapter protein Bam32 antibody; B-cell adapter molecule of 32 kDa antibody; BAM32 antibody; DAPP1 antibody; DAPP1_HUMAN antibody; DKFZp667E0716 antibody; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide antibody; Dual adaptor of phosphotyrosine and 3 phosphoinositides antibody; hDAPP1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from Human BAM32 around the non-phosphorylation site of Y139.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
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基因功能參考文獻：
- we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation. PMID: 21930970
- novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling. PMID: 15247305
- BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells. PMID: 15494510
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亞細胞定位：Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
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組織特異性：Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
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數據庫鏈接：
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