Cd46 Antibody

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Cd46 Polyclonal antibody
Uniprot No.：

O88174
基因名：

Cd46
別名：

Cd46 antibody; McpMembrane cofactor protein antibody; CD antigen CD46 antibody
宿主：

Rabbit
反應種屬：

Mouse
免疫原：

Recombinant Mouse Membrane cofactor protein (45-329AA)
免疫原種屬：

Mus musculus (Mouse)

標記方式：

Non-conjugated

本頁面中的產品，Cd46 Antibody (CSB-PA004939LA01MO)，的標記方式是Non-conjugated。對于Cd46 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA004939LB01MO	Cd46 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004939LC01MO	Cd46 Antibody, FITC conjugated
Biotin	CSB-PA004939LD01MO	Cd46 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
基因功能參考文獻：
1. Changes in CD46 expression may lead to changes in VEGF and play a pathologic role in the development of age-related macular degeneration. PMID: 26161984
2. Our findings provide evidence for expression of CD46 in the mouse eye and a role for CD46 in protection against laser-induced choroidal neovascularization PMID: 25019227
3. This fusion is mediated by the interaction between viral glycoproteins expressed on the membrane of the infected cells and CD46 on the glial targets, and is also observed using cells expressing recombinant MV glycoproteins. PMID: 15920733
4. CD46 isoforms function as receptors for human herpesvirus 6 and measles virus PMID: 12171934
5. Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm and increased male fertility PMID: 12640142
6. CD46 has a role as a receptor for fusion and entry of human herpesvirus 6 into target cells PMID: 12724329
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亞細胞定位：

[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa.; [Isoform 2]: Secreted.
組織特異性：

Present only in testis (at protein level).
數據庫鏈接：

KEGG: mmu:17221

STRING: 10090.ENSMUSP00000123931

UniGene: Mm.12884

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