Ccl9 Antibody

中文名稱：

Ccl9兔多克隆抗體
貨號：

CSB-PA09119A0Rb
規格：

￥440
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Ccl9 Polyclonal antibody
Uniprot No.：

P51670
基因名：

Ccl9
別名：

CCF18 antibody; Ccl9 antibody; CCL9(31-101) antibody; CCL9_MOUSE antibody; Chemokine CC motif ligand 9 antibody; Macrophage inflammatory protein 1-gamma antibody; Macrophage inflammatory protein-related protein 2 antibody; MIP-1-gamma antibody; MRP-2 antibody; SCYA10 antibody; SCYA9 antibody; Small inducible cytokine A9 antibody; Small-inducible cytokine A9 antibody
宿主：

Rabbit
反應種屬：

Mouse
免疫原：

Recombinant Mouse C-C motif chemokine 9 protein (22-114AA)
免疫原種屬：

Mus musculus (Mouse)

標記方式：

Non-conjugated

本頁面中的產品，Ccl9 Antibody (CSB-PA09119A0Rb)，的標記方式是Non-conjugated。對于Ccl9 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA09119B0Rb	Ccl9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA09119C0Rb	Ccl9 Antibody, FITC conjugated
Biotin	CSB-PA09119D0Rb	Ccl9 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
基因功能參考文獻：
1. CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID: 30365155
2. Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID: 28108624
3. we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID: 26483204
4. Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID: 23858028
5. There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID: 20799334
6. Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID: 19883904
7. MRP-2 may be an important contributing factor in the development of atherosclerosis PMID: 12173416
8. CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID: 12397598
9. An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID: 12960300
10. MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID: 15265944
11. Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID: 15961314
12. BCR/ABL repressed CCL9 expression at the transcriptional level PMID: 17160016
13. involved in calcium mobilization and chemotaxis PMID: 11500837
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亞細胞定位：

Secreted.
蛋白家族：

Intercrine beta (chemokine CC) family
組織特異性：

Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
數據庫鏈接：

KEGG: mmu:20308

STRING: 10090.ENSMUSP00000019266

UniGene: Mm.416125

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