CYP39A1 Antibody
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中文名稱：CYP39A1兔多克隆抗體
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貨號：CSB-PA956260
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA956260(CYP39A1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA956260(CYP39A1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：CYP39A1
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別名：24 hydroxycholesterol 7 alpha hydroxylase antibody; 24-hydroxycholesterol 7-alpha-hydroxylase antibody; CP39A_HUMAN antibody; Cyp39a1 antibody; cytochrome P450 family 39; subfamily A polypeptide 1 antibody; Cytochrome P450 39A1 antibody; cytochrome P450 subfamily XXXIX (oxysterol 7 alpha hydroxylase) polypeptide 1 antibody; Cytochrome P450; family 39; subfamily a; polypeptide 1 antibody; hCYP39A1 antibody; Oxysterol 7 alpha hydroxylase antibody; Oxysterol 7-alpha-hydroxylase antibody; oxysterol 7alpha hydroxylase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Fusion protein of Human CYP39A1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
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基因功能參考文獻：
- The CYP39A1 polymorphism rs7761731 may help to identify patients at high risk for treatment related toxicity. PMID: 26475344
- GSTA1 and CYP39A1 were found to be associated with busulfan clearance. When combined, the two haplotypes explained 17% of the variability in busulfan clearance. PMID: 24192117
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亞細胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
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蛋白家族：Cytochrome P450 family
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組織特異性：Liver specific.
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數據庫鏈接：
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