CTSV Antibody
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中文名稱：CTSV兔多克隆抗體
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貨號：CSB-PA214200
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規(guī)格：￥1100
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圖片：
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: NIH/3T3 cells, Primary antibody: CSB-PA214200(CTSV Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：CAT L2 antibody; Cathepsin L2 antibody; Cathepsin U antibody; Cathepsin V antibody; CathepsinL2 antibody; CathepsinU antibody; CathepsinV antibody; CATL 2 antibody; CATL2 antibody; CATL2_HUMAN antibody; CTS L2 antibody; CTS U antibody; CTS V antibody; CTSL 2 antibody; CTSL2 antibody; CTSU antibody; CTSV antibody; MGC125957 antibody; PRO305 antibody; UNQ268 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Fusion protein of Human CTSV
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：Cysteine protease. May have an important role in corneal physiology.
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基因功能參考文獻(xiàn)：
- CTSV is involved in melanosome degradation. PMID: 29654760
- exogenous CTSV inhibited Ang -induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR PMID: 28522343
- Cathepsins V and S may serve as auxiliary diagnostic and/or prognostic markers in thymic epithelial tumors. PMID: 27771373
- E2F1 directly binds to CTSL2 promoter and regulates CTSL2 gene expression. PMID: 23542171
- using cathepsin V and cathepsin L as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V PMID: 24121514
- Cathepsin V expression contributes to the development of dermal fibrosis and vasculopathy in systemic sclerosis. PMID: 23287360
- functions of cathepsin V are controlled by N-glycosylation PMID: 22967898
- Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY) neuropeptides required for neurotransmission in health and neurological diseases. PMID: 22393040
- CTSL2 might be involved in progression of endometrial cancer. PMID: 22452389
- A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri-nucleolar pattern) in thyroid carcinoma cells. PMID: 20536394
- stratum corneum thiol protease is identical with the recently described cathepsin L2 protease. PMID: 12648222
- Cathepsin V is involved in the degradation of invariant chain in human thymus PMID: 12925692
- Cathepsin V has an elastolytic activity and is expressed in activated macrophages PMID: 15192101
- Human cathepsin V compensates for murine cathepsin L in mouse epidermis and hair follicles. PMID: 15679121
- propeptide was found to behave as a tight-binding inhibitor against CatV PMID: 17516850
- Associated with type 1 diabetes and early-onset myasthenia gravis. PMID: 17869649
- angiogenesis inhibition activity on endothelial cells caused by plasminogen processing by cathepsin V PMID: 18163891
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亞細(xì)胞定位：Lysosome.
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蛋白家族：Peptidase C1 family
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組織特異性：Predominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin.
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數(shù)據(jù)庫鏈接：
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