CST1 Antibody
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中文名稱：CST1兔多克隆抗體
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貨號：CSB-PA006088ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA006088ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human salivary gland tissue using CSB-PA006088ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CST1 Polyclonal antibody
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Uniprot No.：
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基因名：CST1
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別名：CST1 antibody; Cystain SAI antibody; Cystain-SA-I antibody; Cystatin 1 antibody; Cystatin-1 antibody; Cystatin-SN antibody; Cystatin1 antibody; Cysteine proteinase inhibitor, type 2 family antibody; CYTN antibody; CYTN_HUMAN antibody; Salivary cystatin SA1 antibody; Salivary cystatin-SA-1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cystatin-SN protein (20-141AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
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基因功能參考文獻：
- Results revealed that CST1 expression was upregulated in colon cancer (CC) compared with normal tissues and contributed to CC cell proliferation. PMID: 29845224
- High CST1 expression is negatively correlated with survival of breast cancer patients. CST1 promotes cell proliferation, clone formation, and metastasis in breast cancer cells. CST1 is a novel potential prognostic biomarker and therapeutic target for breast cancer. PMID: 28523467
- this results identified cystatin 1 as a biomarker in patients with seasonal allergic rhinitis PMID: 28633877
- These results indicate that CST1-mediated extracellular CatB activity enhances tumor development by preventing cellular senescence. PMID: 28383558
- interactions of human family 1 & 2 cystatins with cathepsin L1 PMID: 27764212
- high expression of Cystatin SN is a significant prognostic indicator of a higher rate of recurrence, metastatic risk, and poor survival in patients with surgically resected NSCLCs. PMID: 25648368
- In conclusion, our data suggest that CST1 might contribute to the proliferation of pancreatic cancer cells and could be a potential biomarker for the early detection of pancreatic cancer. PMID: 25577248
- CST1 may contribute to inactivation of protease allergens and help re-establish homeostasis of the nasal membranes. PMID: 23950865
- CST1 expression at both the messenger RNA and protein levels was barely detected in control cells, which included early passage proliferating, quiescent, or immortal human fibroblasts PMID: 21636832
- Murine monoclonal antibodies were made which can distinguish between CST1 and CST2. PMID: 15829315
- CST1 might be highly involved in gastric tumorigenesis and regulate the proteolytic activity of cysteine proteases. PMID: 19463800
- Identification of Cystatin SN as a novel tumor marker for colorectal cancer. PMID: 19513549
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亞細胞定位：Secreted.
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蛋白家族：Cystatin family
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組織特異性：Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid.
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數據庫鏈接：
