CRISP2 Antibody
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中文名稱：CRISP2兔多克隆抗體
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貨號(hào)：CSB-PA005975ESR1HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: CRISP2 antibody at 12μg/ml + Rat gonad tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 32 kDa
Observed band size: 28 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005975ESR1HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CRISP2 Polyclonal antibody
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Uniprot No.：
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基因名：CRISP2
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別名：Cancer/testis antigen 36 antibody; CRIS2_HUMAN antibody; CRISP 2 antibody; CRISP-2 antibody; CRISP2 antibody; CT36 antibody; Cysteine rich secretory protein 2 antibody; Cysteine-rich secretory protein 2 antibody; GAPDL5 antibody; Glyceraldehyde 3 phosphate dehydrogenase like 5 antibody; Testis specific protein 1 (probe H4 1 p3 1) antibody; Testis specific protein TPX1 antibody; Testis-specific protein TPX-1 antibody; TPX1 antibody; TSP1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human, Rat
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免疫原：Recombinant Human Cysteine-rich secretory protein 2 protein (22-243AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:200-1:1000 IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
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基因功能參考文獻(xiàn)：
- low expression of CRISP2 protein rather than its mRNA was observed in the ejaculated spermatozoa from asthenoteratozoospermic patients as compared with normozoospermic males PMID: 27517483
- Results identified CRISP2 as a potential binding protein of PSP94 from human sperm. PMID: 27161017
- Crisp2 genetic defects in sperm from humans and mice result in male infertility. PMID: 26786179
- Preliminary insight into the mechanism leading to the reduced CRISP2 expression in asthenozoospermia, offering a potential therapeutic target for treating male infertility or for male contraception. PMID: 25505194
- Study shows the re-association of sperm acrosomal CRISP2 at the EqS during the acrosome reaction. Data showed that F-actin is not involved in the relocalization of CRISP2. Found that basic,but not acidic, conditions can solubilize CRISP2 from sperm cells. PMID: 23661501
- CRISP2 rescues the phenotype of yeast mutants lacking Pry function and purified CRISP2 binds cholesterol in vitro, indicating that lipid binding is a conserved function of the CAP superfamily proteins. PMID: 23027975
- The down-regulation of CRISP2 mRNA and protein expressions in the sperm of asthenospermia patients may be closely related with decreased sperm motility. PMID: 21485539
- Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included decreased CRISP2&3. PMID: 20625511
- TPX1 is a component of the sperm acrosome that remains associated with sperm after capacitation and acrosome reaction , and is relevant for sperm-oocyte interaction. PMID: 15734896
- The protein level and localization of TPX1 were altered in patients with spermatogenic arrest and in infertile men with oligoasthenoteratospermia syndrome. PMID: 16759931
- Polymorphisms within the CRISP2 gene have no significant association with male infertility. PMID: 18550510
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亞細(xì)胞定位：Secreted.
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蛋白家族：CRISP family
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組織特異性：Testis and epididymis.
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數(shù)據(jù)庫(kù)鏈接：
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