CRHR1 Antibody

中文名稱：

CRHR1兔多克隆抗體
貨號：

CSB-PA005965YA01HU
規格：

￥440
圖片：
IHC image of CSB-PA005965YA01HU diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of Hela cells with CSB-PA005965YA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CRHR1 Polyclonal antibody
Uniprot No.：

P34998
基因名：

CRHR1
別名：

Corticotropin releasing factor type 1 receptor antibody; corticotropin releasing hormone receptor 1 antibody; Corticotropin-releasing factor receptor 1 antibody; Corticotropin-releasing hormone receptor 1 antibody; CRF R antibody; crf receptor 1 antibody; crf receptor type 1 antibody; crf type 1 antibody; CRF-R antibody; CRF-R-1 antibody; CRF-R1 antibody; CRF1 antibody; CRFR antibody; CRFR-1 antibody; CRFR1 antibody; CRFR1_HUMAN antibody; CRH-R-1 antibody; CRH-R1 antibody; CRH-R1h antibody; CRHR antibody; Crhr1 antibody; CRHR1f antibody; CRHR1L antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Corticotropin-releasing factor receptor 1 protein (24-121AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CRHR1 Antibody (CSB-PA005965YA01HU)，的標記方式是Non-conjugated。對于CRHR1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA005965YB01HU	CRHR1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005965YC01HU	CRHR1 Antibody, FITC conjugated
Biotin	CSB-PA005965YD01HU	CRHR1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:500-1:1000
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis.
蛋白家族：

G-protein coupled receptor 2 family
組織特異性：

Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
數據庫鏈接：

HGNC: 2357

OMIM: 122561

KEGG: hsa:104909134

STRING: 9606.ENSP00000381333

UniGene: Hs.417628

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