CPT1C Antibody

中文名稱：

CPT1C兔多克隆抗體
貨號：

CSB-PA855048LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: Hela whole cell lysate, Mouse liver tissue, Mouse lung tissue
All lanes: CPT1C antibody at 2.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 91, 90, 81 kDa
Observed band size: 91 kDa

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA855048LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA855048LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CPT1C Polyclonal antibody
Uniprot No.：

Q8TCG5
基因名：

CPT1C
別名：

brain isoform antibody; Carnitine acyltransferase like protein 1 antibody; Carnitine acyltransferase like protein1 antibody; Carnitine O palmitoyltransferase 1 brain isoform antibody; Carnitine O palmitoyltransferase I; brain isoform antibody; Carnitine O-palmitoyltransferase 1 antibody; Carnitine O-palmitoyltransferase I antibody; Carnitine palmitoyltransferase 1; brain antibody; Carnitine palmitoyltransferase 1C antibody; Carnitine palmitoyltransferase I related C antibody; Carnitine palmitoyltransferase1C antibody; CAT L1 antibody; CATL 1 antibody; CATL1 antibody; CPT 1 like pseudogene antibody; Cpt 1c antibody; CPT 1P antibody; CPT I C antibody; CPT IC antibody; Cpt1 c antibody; CPT1 like pseudogene antibody; CPT1-B antibody; Cpt1c antibody; CPT1C_HUMAN antibody; CPT1P antibody; CPTI-B antibody; CPTIC antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform protein (699-803AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CPT1C Antibody (CSB-PA855048LA01HU)，的標記方式是Non-conjugated。對于CPT1C Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA855048LB01HU	CPT1C Antibody, HRP conjugated	ELISA
FITC	CSB-PA855048LC01HU	CPT1C Antibody, FITC conjugated
Biotin	CSB-PA855048LD01HU	CPT1C Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

May play a role in lipid metabolic process.
基因功能參考文獻：
1. Depletion of PPARalpha resulted in low CPT1C expression. PMID: 28334197
2. CPT1C binds malonyl-CoA and long-chain acyl-CoA suggest that it is a sensor of lipid metabolism in neurons, where it appears to impact ceramide and triacylglycerol metabolism. [review] PMID: 26708865
3. CPT1c is found in brain regions that are related to food intake and neuropsychiatric disease. CPT1c affects ceramide levels, endocannabionoids, and oxidative processes and may play an important role in various brain functions such as learning. PMID: 26041663
4. CPT1C mutation associated with novel form of pure autosomal dominant hereditary spastic paraplegia. PMID: 25751282
5. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C. PMID: 24618825
6. Data suggest that an involvement of CPT1C in cellular energy-sensing pathways and provide evidence for a role of CPT1C in hypothalamic regulation of energy homeostasis. PMID: 21961029
7. cells can use a novel mechanism involving CPT1C and fatty acid metabolism to protect against metabolic stress PMID: 21576264
8. CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity PMID: 18192268
9. Accumulation of 3-hydroxylated intermediates of long-chain fatty acids may contribute to the pathogenesis of retinopathy in MTP deficiencies. PMID: 18385088
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相關疾病：

Spastic paraplegia 73, autosomal dominant (SPG73)
亞細胞定位：

Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum.
蛋白家族：

Carnitine/choline acetyltransferase family
組織特異性：

Expressed predominantly in brain and testis. Expressed in motor neurons.
數據庫鏈接：

HGNC: 18540

OMIM: 608846

KEGG: hsa:126129

STRING: 9606.ENSP00000319343

UniGene: Hs.112195

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