CPA6 Antibody
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中文名稱：CPA6兔多克隆抗體
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貨號：CSB-PA005880LA01HU
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規(guī)格：￥440
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CPA6 Polyclonal antibody
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Uniprot No.：
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基因名：CPA6
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別名：CPA6 antibody; CPAHCarboxypeptidase A6 antibody; EC 3.4.17.- antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Carboxypeptidase A6 protein (130-437AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁面中的產(chǎn)品，CPA6 Antibody (CSB-PA005880LA01HU)，的標(biāo)記方式是Non-conjugated。對于CPA6 Antibody，我們還提供其他標(biāo)記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine.
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基因功能參考文獻(xiàn)：
- Common variants in PRPF31 and CPA6 were associated with worse and better metformin response, respectively. PMID: 29650774
- these mutations in CPA6 are deleterious and provide further evidence for the involvement of CPA6 mutations in the predisposition for several types of epilepsy. PMID: 25875328
- Significantly higher levels of DNA methylation are found in the CPA6 promoter in focal epilepsy and febrile seizure patients. PMID: 24290490
- These results provide further evidence for the involvement of CPA6 mutations in human epilepsy. PMID: 23105115
- CPA6 mutatins are genetically linked to an autosomal recessive familial form of febrile seizures and temporal lobe epilepsy (TLE), and are associated with sporadic TLE cases. PMID: 21922598
- Substrate specificity of human carboxypeptidase A6 PMID: 20855895
- The CPAH gene was interrupted in a patient with DURS carrying a translocation break point in the DURS1 region on chromosome 8q13. PMID: 12454025
- CPA6 may have a role in the regulation of neuropeptides in the extracellular environment within the olfactory bulb and other parts of the brain PMID: 18178555
- Thrombin activation of osteopontin (OPN) (resulting in OPN-R) and its subsequent inactivation by thrombin-activatable carboxypeptidase B (generating OPN-L) occurs locally within inflamed joints in rheumatoid arthritis. PMID: 19790060
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相關(guān)疾病：Epilepsy, familial temporal lobe, 5 (ETL5); Febrile seizures, familial, 11 (FEB11)
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亞細(xì)胞定位：Secreted, extracellular space, extracellular matrix.
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蛋白家族：Peptidase M14 family
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組織特異性：Expressed in the hippocampus, nucleus raphe, and cortex.
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數(shù)據(jù)庫鏈接：
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