The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
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貨期:
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
基因功能參考文獻:
COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485