CORO7 Antibody
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中文名稱：CORO7兔多克隆抗體
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貨號：CSB-PA005819LA01HU
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規(guī)格：￥440
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CORO7 Polyclonal antibody
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Uniprot No.：
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基因名：CORO7
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別名：0610011B16Rik antibody; 70 kDa WD repeat tumor rejection antigen homolog antibody; CORO 7 antibody; Coro7 antibody; CORO7_HUMAN antibody; Coronin-7 antibody; Coronin7 antibody; Crn7 antibody; FLJ22021 antibody; FLJ44188 antibody; POD1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Coronin-7 protein (630-900AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，CORO7 Antibody (CSB-PA005819LA01HU)，的標記方式是Non-conjugated。對于CORO7 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
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基因功能參考文獻：
- Obese children had significantly lower methylation levels at a CpG site located near coronin 7 (CORO7), which encodes a tryptophan-aspartic acid dipeptide (WD)-repeat containing protein most likely involved in Golgi complex morphology and function PMID: 25887538
- Results show that enforced targeting of Crn7 to TGN 9trans-Golgi network) bypasses the requirement of K33-ubiquitination for TGN-pool F-actin assembly and post-Golgi trafficking. PMID: 24768539
- Data show that CRN7 interacted with Cullin1 and Roc1 to form a novel SCF-like E3 complex. PMID: 21130766
- role in the organization of intracellular membrane compartments and vesicular trafficking rather than in remodeling the cytoskeleton PMID: 15327992
- Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi PMID: 16905771
- Sequential events of protein interaction and posttranslational modification result in the membrane targeting of Crn7. PMID: 18581049
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亞細胞定位：Golgi apparatus membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.
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蛋白家族：WD repeat coronin family
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組織特異性：Widely expressed. Expressed in the spleen, peripheral leukocytes, testes, brain, thymus and small intestine.
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數(shù)據(jù)庫鏈接：
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