COL6A6 Antibody

中文名稱：

COL6A6兔多克隆抗體
貨號：

CSB-PA409861LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA409861LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA409861LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) COL6A6 Polyclonal antibody
Uniprot No.：

A6NMZ7
基因名：

COL6A6
別名：

COL6A6Collagen alpha-6(VI) chain antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Collagen alpha-6(VI) chain protein (430-982AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，COL6A6 Antibody (CSB-PA409861LA01HU)，的標記方式是Non-conjugated。對于COL6A6 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA409861LB01HU	COL6A6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA409861LC01HU	COL6A6 Antibody, FITC conjugated
Biotin	CSB-PA409861LD01HU	COL6A6 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Collagen VI acts as a cell-binding protein.
基因功能參考文獻：
1. Study identified SNPs in COL6A6 associated with atopic dermatitis suggesting that COL6A6 variants may constitute candidate risk factors for early-onset atopic dermatitis. PMID: 28125976
2. A whole-exome sequencing approach led to identification of a deletion in RHO through detection of a new linked variant in COL6A6 in autosomal dominant retinitis pigmentosa. PMID: 26321861
3. Reduced collagen VI alpha6 chain expression in the skeletal muscle is associated with collagen VI-related myopathies. PMID: 24907562
4. The collagen VI alpha6 chain, but not the alpha5 chain, is up-regulated in dystrophic muscles. PMID: 22226732
5. collagen VI alpha 6 is an important basal lamina component involved in the regulation of epithelial cell behavior most notably as a regulator of epithelial cell-fibronectin interactions PMID: 21406227
6. localization of alpha5, and to a lesser extent alpha6, is restricted to the papillary dermis, where the protein mainly colocalizes with collagen fibrils; both chains were found around blood vessels PMID: 20882040
7. The discovery of three additional collagen VI chains doubles the collagen VI family and adds a layer of complexity to collagen VI assembly and function in the extracellular matrix. PMID: 18400749
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Type VI collagen family
數據庫鏈接：

HGNC: 27023

OMIM: 616613

KEGG: hsa:131873

STRING: 9606.ENSP00000351310

UniGene: Hs.591282

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