CNTROB Antibody
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中文名稱：CNTROB兔多克隆抗體
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貨號：CSB-PA090803
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規(guī)格：￥1100
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圖片：
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA090803(CNTROB Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CNTROB
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別名：9830165K03Rik antibody; Centrobin antibody; centrobin; centrosomal BRCA2 interacting protein antibody; Centrosomal BRCA2 interacting protein antibody; Centrosomal BRCA2-interacting protein antibody; CNTRB_HUMAN antibody; Cntrob antibody; LIP8 antibody; LYST interacting protein 8 antibody; LYST-interacting protein 8 antibody; LYST-interacting protein LIP8 antibody; PP1221 antibody; RGD1307488 antibody; RP23 26L6.9 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Fusion protein of Human CNTROB
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
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基因功能參考文獻：
- cytoplasmic centrobin has roles in noncentrosomal microtubule formation in specific cell types and during the cell cycle PMID: 26083938
- it is proposed that Centrobin might regulate microtubule nucleation and organization by controlling the amount of pericentriolar matrix PMID: 23442802
- NEK2 phosphorylation antagonizes the microtubule stabilizing activity of centrobin. PMID: 23291182
- Our results indicate that genetic polymorphisms of centrobin and Nek2 are related to breast cancer susceptibility in Chinese Han women. PMID: 23001753
- Centrobin facilitates the elongation and stability of centrioles via its interaction with tubulins. PMID: 21576394
- Data propose that centrobin functions as a microtubule stabilizing factor and PLK1 enhances centrobin activity for proper spindle formation during mitosis. PMID: 20511645
- a requirement of Centrobin in maintaining centrosome integrity, which in turn promotes anchoring of mitotic spindle to the centrosomes. PMID: 20190801
- Inhibition of p38 activity or downregulation of p38 expression could overcome the cell-cycle arrest caused by centrobin depletion. PMID: 20085806
- Centrobin is a centriole-associated protein that asymmetrically localizes to the daughter centriole. PMID: 16275750
- Results report that NIP2, previously identified as centrobin, is a novel substrate of Nek2, and that NIP2 has a role in stabilizing the microtubule structure. PMID: 17535851
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亞細胞定位：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.
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組織特異性：Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
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數(shù)據(jù)庫鏈接：
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