CLDND1 Antibody

說(shuō)明書(shū)

中文名稱(chēng)：

CLDND1兔多克隆抗體
貨號(hào)：

CSB-PA873687LA01HU
規(guī)格：

￥440
圖片：
Immunofluorescence staining of U251 cells with CSB-PA873687LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) CLDND1 Polyclonal antibody
Uniprot No.：

Q9NY35
基因名：

CLDND1
別名：

CLDND1; C3orf4; HSPC174; PSEC0054; UNQ2511/PRO6000; Claudin domain-containing protein 1; Membrane protein GENX-3745
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Claudin domain-containing protein 1 protein (26-140AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，CLDND1 Antibody (CSB-PA873687LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于CLDND1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱(chēng)	應(yīng)用
HRP	CSB-PA873687LB01HU	CLDND1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA873687LC01HU	CLDND1 Antibody, FITC conjugated
Biotin	CSB-PA873687LD01HU	CLDND1 Antibody, Biotin conjugated	ELISA

克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻(xiàn)：
1. suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability PMID: 28244141
2. Z38 was overexpressed in clinical patients with RCC and was associated with RCC stage. Knockdown of Z38 in A498 and ACHIN cells inhibited cell proliferation and metastasis PMID: 28849012
3. findings strongly suggest that CLDND1 is a direct RORalpha target PMID: 28130419
4. CLDND1 as a novel survival factor in basal-like breast cancer cell lines PMID: 26083392
5. A cDNA library consisting of 220 upregulated genes in tumour tissue was established and named as LSCC. Differential expression was confirmed in five of these genes, including IGFBP5, SQLE, RAP2B, CLDN1, and TBL1XR1. PMID: 17316888
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亞細(xì)胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

PMP-22/EMP/MP20 family
組織特異性：

Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 1322

KEGG: hsa:56650

STRING: 9606.ENSP00000388457

UniGene: Hs.531371

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