CKMT2 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P17540
基因名：

CKMT2
別名：

CKMT 2 antibody; Basic-type mitochondrial creatine kinase antibody; CKMT2 antibody; CPK antibody; Creatine kinase mitochondrial 2 antibody; Creatine kinase mitochondrial 2 (sarcomeric) antibody; Creatine kinase S-type antibody; creatine kinase S-type, mitochondrial antibody; Creatine kinase, sarcomeric mitochondrial antibody; KCRS_HUMAN antibody; Mib CK antibody; Mib-CK antibody; mitochondrial antibody; OTTHUMP00000147542 antibody; S-MtCK antibody; Sarcomeric mitochondrial creatine kinase antibody; SMTCK antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human sMtCK.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IHC, IF, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
基因功能參考文獻(xiàn)：
1. three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components PMID: 15044463
2. After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase. PMID: 16020522
3. CK2alpha has a role in progression of acute myeloid leukemia PMID: 17289898
亞細(xì)胞定位：

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
蛋白家族：

ATP:guanido phosphotransferase family
組織特異性：

Sarcomere-specific. Found only in heart and skeletal muscles.
數(shù)據(jù)庫鏈接：

HGNC: 1996

OMIM: 123295

KEGG: hsa:1160

STRING: 9606.ENSP00000254035

UniGene: Hs.80691

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