CHST2 Antibody
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中文名稱：CHST2兔多克隆抗體
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貨號(hào)：CSB-PA001644
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of Jurkat cells using CHST2 Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CHST2
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別名：CHST2 antibody; GN6STCarbohydrate sulfotransferase 2 antibody; EC 2.8.2.- antibody; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2 antibody; GST-2 antibody; N-acetylglucosamine 6-O-sulfotransferase 1 antibody; GlcNAc6ST-1 antibody; Gn6ST-1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from the N-terminal region of Human CHST2.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
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基因功能參考文獻(xiàn)：
- GlcNAc6ST1 is up-regulated in the brains of Alzheimer's disease patients. PMID: 28320965
- A method for O-GlcNAc detection using in vitro sulfation with two N-acetylglucosamine (GlcNAc)-specific sulfotransferases, carbohydrate sulfotransferase 2 and carbohydrate sulfotransferase 4. PMID: 24799377
- report the sites at which N-Acetylglucosamine-6-sulfotransferase-1 is modified with N-linked glycans and the effects that each glycan has on enzyme activity, specificity, and localization.[N-Acetylglucosamine-6-sulfotransferase-1] PMID: 19571171
- is distributed throughout the Golgi apparatus and orchestrates the biosynthesis of L-selectin ligands PMID: 12855678
- A novel tumor antigen that is specifically expressed in ovarian mucinous, clear cell and papillary serous adenocarcinomas. PMID: 16897186
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亞細(xì)胞定位：Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein.
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蛋白家族：Sulfotransferase 1 family, Gal/GlcNAc/GalNAc subfamily
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組織特異性：Widely expressed. Highly expressed in bone marrow, peripheral blood leukocytes, spleen, brain, spinal cord, ovary and placenta. Expressed by high endothelial cells (HEVs) and leukocytes.
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數(shù)據(jù)庫(kù)鏈接：
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