CETN1 Antibody

說明書

中文名稱：

CETN1兔多克隆抗體
貨號：

CSB-PA613263DSR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA613263DSR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CETN1 Polyclonal antibody
Uniprot No.：

Q12798
基因名：

CETN1
別名：

Caltractin antibody; Caltractin isoform 2 antibody; CEN 1 antibody; CEN1 antibody; Centrin EF hand protein 1 antibody; Centrin-1 antibody; Centrin1 antibody; CETN 1 antibody; CETN antibody; CETN1 antibody; CETN1_HUMAN antibody; EF hand protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Centrin-1 protein (1-172AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a fundamental role in microtubule-organizing center structure and function. Plays a role in sperm cilia formation.
基因功能參考文獻：
1. important spectral and hydrodynamic characteristics of human Centrin-1, accounting that HsCentrin-1 has moderate affinity for Ca(2+). Centrin-1 does not gain structure as seen by far- and near-UV circular dichroism, rather there is a loss of ellipticity, though inconsiderable upon binding Ca(2+). PMID: 27235176
2. A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin. PMID: 26923803
3. CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis. PMID: 25261648
4. These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis. PMID: 16760425
亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
蛋白家族：

Centrin family
數據庫鏈接：

HGNC: 1866

OMIM: 603187

KEGG: hsa:1068

STRING: 9606.ENSP00000319052

UniGene: Hs.122511

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