CDK19 Antibody
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中文名稱：CDK19兔多克隆抗體
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貨號：CSB-PA005003GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CDK19
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別名：bA346C16.3 antibody; CDC2 related protein kinase 6 antibody; CDC2-related protein kinase 6 antibody; CDC2L6 antibody; CDK11 antibody; Cdk19 antibody; CDK19_HUMAN antibody; CDK8 like cyclin dependent kinase antibody; Cell division cycle 2 like 6 (CDK8 like) antibody; Cell division cycle 2 like protein kinase 6 antibody; Cell division cycle 2-like protein kinase 6 antibody; Cell division protein kinase 19 antibody; Cyclin dependent kinase (CDC2 like) 11 antibody; Cyclin dependent kinase 11 antibody; Cyclin dependent kinase 19 variant 2 antibody; Cyclin-dependent kinase 11 antibody; Cyclin-dependent kinase 19 antibody; Death preventing kinase antibody; Death-preventing kinase antibody; KIAA1028 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human CDC2L6
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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基因功能參考文獻：
- Genes coregulated by CDK8/19 and NFkappaB include IL8, CXCL1, and CXCL2. PMID: 28855340
- Moreover, it identified CDK19 and CDK8 to be specifically overexpressed during prostate cancer progression, highlighting their potential as novel therapeutic targets in advanced prostate cancer. PMID: 27678455
- High CDK19 expression is associated with osteosarcoma. PMID: 28416637
- On stimulation of TLR9, CDK8/19 positively regulates inflammatory gene transcription in cooperation with NF-kappaB and C/EBPbeta. PMID: 28151579
- Data suggest that, during neurogenesis, Mediator complex cyclin-dependent kinases (CDK8, CDK19) interact directly with PRC2 (polycomb repressive complex 2) subunit EZH2 (enhancer of zeste homolog 2), as well as SUZ12 (suppressor of zeste 12 homolog). PMID: 26002960
- Mediator-associated kinases CDK8 and CDK19 restrain increased activation of key super-enhancer-associated genes in acute myeloid leukaemia (AML) cells PMID: 26416749
- Microarrays identified target genes for each CDK, and we selected six genes: two target genes of CDK8, two target genes of CDK19 and two genes that were targets for both. PMID: 22117896
- CDK8 and CDK19, individually interact with PRMT5 and WDR77, and their interactions with PRMT5 cause transcriptional repression of C/EBPbeta target genes. PMID: 23749998
- plays a role in mechanisms of transcriptional regulation upon protein phosphorylation. (review) PMID: 20408451
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亞細胞定位：Cytoplasm. Cytoplasm, perinuclear region. Nucleus.
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蛋白家族：Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
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數(shù)據(jù)庫鏈接：
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