CDH22 Antibody
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中文名稱：CDH22兔多克隆抗體
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貨號：CSB-PA050035
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：CDH22
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別名：CDH22 antibody; C20orf25 antibody; Cadherin-22 antibody; Pituitary and brain cadherin antibody; PB-cadherin antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human Cadherin-22.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, IF, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.
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基因功能參考文獻：
- cadherin-22 is upregulated in hypoxia via mTORC1-independent translational control by the initiation factor eIF4E2 functioning as a hypoxia-specific cell-surface molecule involved in cancer cell migration, invasion and adhesion. PMID: 28991229
- Results present evidence that CDH22 is hypermethylated and its expression is downregulated in breast cancer. PMID: 28149335
- PRL-3 promoted downregulation of CDH22 expression. PMID: 19440036
- Our results reveal for the first time a new role of CDH22 in progression of colorectal cancer. PMID: 19546606
- This paper deals primarily with the rat ortholog of the human CDH22 gene. PMID: 8626716
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亞細胞定位：Cell membrane; Single-pass type I membrane protein.
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數據庫鏈接：
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