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中文名稱：
CCT6A兔多克隆抗體
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貨號：
CSB-PA004250
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規格：
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圖片：
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其他：
產品詳情
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Uniprot No.：
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基因名：
CCT6A
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別名：
CCT6A antibody; CCT6 antibody; CCTZ antibody; T-complex protein 1 subunit zeta antibody; TCP-1-zeta antibody; Acute morphine dependence-related protein 2 antibody; CCT-zeta-1 antibody; HTR3 antibody; Tcp20 antibody
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宿主：
Rabbit
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反應種屬：
Human,Mouse,Rat
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免疫原：
Synthesized peptide derived from the Internal region of Human TCP-1 ζ.
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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抗體亞型：
IgG
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純化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：
Liquid
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應用范圍：
WB, IHC, ELISA
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推薦稀釋比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IHC |
1:100-1:300 |
| ELISA |
1:10000 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
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基因功能參考文獻：
- High expression of CCT6A is associated with Non-Small Cell Lung Cancer. PMID: 28104536
- selective inhibition of SMAD3 or CCT6A efficiently suppresses TGF-beta-mediated metastasis. Findings provide a mechanism that directs TGF-beta signaling toward its prometastatic arm and may contribute to the development of therapeutic strategies targeting TGF-beta for non-small-cell lung carcinoma. PMID: 28375158
- These data suggest that CCT6A is a novel autoantigen recognized by Vdelta2 gammadelta T cells, which deepens our understanding of mechanisms in autoimmune diseases. PMID: 27489109
- identified genes, which include Tcp20, may play important role in conferring radioresistance to oral squamous cell carcinoma and could be useful in identifying cases with more radioresistance PMID: 16211299
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亞細胞定位：
Cytoplasm.
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蛋白家族：
TCP-1 chaperonin family
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數據庫鏈接：
Most popular with customers
Western Blot analysis of HepG2 cells using TCP-1 ζ Polyclonal Antibody
