CCDC8 Antibody
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中文名稱：CCDC8兔多克隆抗體
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貨號：CSB-PA880938LA01HU
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規格：￥440
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圖片：
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Immunofluorescent analysis of Hela cells using CSB-PA880938LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) -
Western Blot
Positive WB detected in: Mouse liver tissue
All lanes: CCDC8 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 60 kDa
Observed band size: 60 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCDC8 Polyclonal antibody
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Uniprot No.：
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基因名：CCDC8
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別名：CCDC8 antibody; CCDC8_HUMAN antibody; Coiled coil domain containing 8 antibody; Coiled-coil domain-containing protein 8 antibody; DKFZp564K0322 antibody; ENSMUSG00000041117 antibody; MGC72567 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human Coiled-coil domain-containing protein 8 protein (214-513AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，CCDC8 Antibody (CSB-PA880938LA01HU)，的標記方式是Non-conjugated。對于CCDC8 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:2000-1:5000 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome.
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基因功能參考文獻：
- Variants near TTN and CCDC8 were associated with KI67 expression, and rs2288563 and rs2562832 in TTN are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients. PMID: 28700999
- CCDC8 may suppress the invasion and metastasis of non-small cell lung cancer cells. PMID: 27342910
- CUL7, OBSL1 and CCDC8 modulate the alternative splicing of the INSR PMID: 24711643
- The CUL7, OBSL1, and CCDC8 proteins form a 3M complex that functions in maintaining microtubule and genome integrity and normal development. PMID: 24793695
- Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling. PMID: 23018678
- discussion of roles of CCDC8, CUL7 (cullin 7), and OBSL1 (obscurin-like 1) in growth and development using findings from patients with Miller-McKusick-Malvaux syndrome and Silver-Russell syndrome [REVIEW] PMID: 22156540
- p90 is a critical cofactor for p53-mediated apoptosis through promoting Tip60-mediated p53 acetylation. PMID: 22084066
- We propose that CUL7, OBSL1, and CCDC8 are members of a pathway controlling mammalian growth. PMID: 21737058
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相關疾病：3M syndrome 3 (3M3)
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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組織特異性：Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver.
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數據庫鏈接：
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