CCDC66 Antibody
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中文名稱：CCDC66兔多克隆抗體
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貨號：CSB-PA004728LA01HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA004728LA01HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CCDC66 Polyclonal antibody
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Uniprot No.：
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基因名：CCDC66
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別名：CCD66_HUMAN antibody; Ccdc66 antibody; Coiled coil domain containing 66 antibody; Coiled coil domain containing protein 66 antibody; Coiled-coil domain-containing protein 66 antibody; DKFZp686C0433 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Coiled-coil domain-containing protein 66 protein (87-286AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，CCDC66 Antibody (CSB-PA004728LA01HU)，的標記方式是Non-conjugated。對于CCDC66 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites. Plays a role in retina morphogenesis and/or homeostasis.
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基因功能參考文獻：
- Results associate a distinct retinal dystrophy phenotype with nicotinamide-nucleotide adenylyltransferase 1 protein (NMNAT1) mutation and suggest coiled-coil domain containing 66 (CCDC66) should not be considered a retinal dystrophy candidate gene. PMID: 28369829
- In-depth characterization revealed that circCCDC66 exerts its function via regulation of a subset of oncogenes, and knockdown of circCCDC66 inhibited tumor growth and cancer invasion in xenograft and orthotopic mouse models, respectively. Taken together, these findings highlight a novel oncogenic function of circRNA in cancer progression and metastasis. PMID: 28249903
- this study identifies CCDC66 as a targeting factor for centrosome and cilium proteins PMID: 28235840
- Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
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亞細胞定位：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
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組織特異性：Widely expressed (at protein level). Expressed in retina, mainly in photoreceptors but also in outer plexiform and ganglion cell layers (at protein level).
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數據庫鏈接：
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