CAPN6 Antibody, Biotin conjugated
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中文名稱：CAPN6兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA897594LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CAPN6 Polyclonal antibody
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Uniprot No.：
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基因名：CAPN6
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別名：CALP M antibody; Calpain-6 antibody; Calpain-like protease X-linked antibody; Calpamodulin antibody; CalpM antibody; CAN6_HUMAN antibody; CANP X antibody; CANPX antibody; CAPN 6 antibody; Capn6 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Calpain-6 protein (195-494AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.
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基因功能參考文獻：
- High CAPN6 expression is associated with liver cancer. PMID: 26375440
- CAPN6 promotes atherogenicity in inflamed macrophages by disturbing CWC22/EJC systems. PMID: 27525442
- syndecan-2 exerts its pro-apoptotic function through modulation of the endothelin-1/NFkappaB signaling and through downregulation of calpain-6. PMID: 21681744
- results indicated that calpain 6 supported tumorigenesis by inhibiting apoptosis and facilitating angiogenesis. To our knowledge, this result is the first evidence implicating calpain 6 in tumorigenesis PMID: 18657900
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亞細胞定位：Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle.
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蛋白家族：Peptidase C2 family
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組織特異性：Expressed only in placenta.
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數據庫鏈接：
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