CA8 Antibody

說明書

中文名稱：

CA8兔多克隆抗體
貨號：

CSB-PA004379GA01HU
規格：

￥3,900
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

Uniprot No.：

P35219
基因名：

CA8
別名：

CA VIII antibody; CA-VIII antibody; Ca8 antibody; CAH8_HUMAN antibody; CALS antibody; Carbonic anhydrase related protein antibody; Carbonic anhydrase VIII antibody; Carbonic anhydrase-related protein antibody; CARP antibody; MGC120502 antibody; MGC99509 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human CA8
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Does not have a carbonic anhydrase catalytic activity.
基因功能參考文獻：
1. we observed increased expression of CA8 in more aggressive types of human osteosarcoma (OS) cells and found that CA8 expression is correlated with disease stages, such that more intense expression occurs in the disease late stage PMID: 26711783
2. CA8 overexpression desensitizes neuronal cells to STS induced apoptotic stress and increases cell migration and invasion ability in neuronal cells. PMID: 24794067
3. Overexpression of CA8 in MERRF cybrids significantly decreases cell death. PMID: 24476000
4. This report expands the neurological and radiological phenotype associated with CA8 mutations. PMID: 21812104
5. review article describes the previous data on CARP VIII, including its structure, role in neurodegeneration and cancer; and bioinformatic and expression analyses. PMID: 20819067
6. Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing PMID: 19360879
7. Overexpression of Carbonic anhydrase-related protein VIII promotes colon cancer cell growth PMID: 17219437
8. The results suggest that the variations of CA8 and CA10 loci may be important determinants of osteoporosis in Japanese women. PMID: 19172221
9. Consanguineous Iraqi family in which affected siblings had mild mental retardation and congenital ataxia characterized by quadrupedal gait. The mutation S100P is associated with proteasome-mediated degradation, and presumably represents a null mutation. PMID: 19461874
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相關疾病：

Cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3)
蛋白家族：

Alpha-carbonic anhydrase family
數據庫鏈接：

HGNC: 1382

OMIM: 114815

KEGG: hsa:767

STRING: 9606.ENSP00000314407

UniGene: Hs.654388

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