CA3 Antibody

中文名稱：

CA3兔多克隆抗體
貨號：

CSB-PA004371LA01HU
規格：

￥440
圖片：
Western blot
All lanes: CA3 antibody at 2µg/ml
Lane 1: Hela whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: K562 whole cell lysate
Lane 4: NIH/3T3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004371LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA004371LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CA3 Polyclonal antibody
Uniprot No.：

P07451
基因名：

CA3
別名：

CA III antibody; CA-III antibody; Ca3 antibody; CAH3_HUMAN antibody; CAIII antibody; Car3 antibody; Carbonate dehydratase III antibody; Carbonic anhydrase 3 antibody; Carbonic anhydrase III antibody; Carbonic anhydrase III muscle specific antibody; EC 4.2.1.1 antibody; Epididymis secretory sperm binding protein Li 167mP antibody; HEL S 167mP antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Carbonic anhydrase 3 protein (2-260AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CA3 Antibody (CSB-PA004371LA01HU)，的標記方式是Non-conjugated。對于CA3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA004371LB01HU	CA3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004371LC01HU	CA3 Antibody, FITC conjugated
Biotin	CSB-PA004371LD01HU	CA3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Reversible hydration of carbon dioxide.
基因功能參考文獻：
1. CAIII and Hsp70 expressions were higher in LPRD patients that in non-LPRD patients, suggesting the possibility as one of biomomarker in LPRD diagnosis. PMID: 26847302
2. this study detected the formation and colocalization of 6-nitrotryptophan-containing proteins and CAIII in the skin of atopic dermatitis patients, not only in the lesional part but also in the nonlesional part, through histochemical analyses PMID: 24838180
3. Report that anti-CAIII antibodies may be useful for diagnosing microscopic polyangiitis. PMID: 23981757
4. The carbonic anhydrase CA3 isoform displayed an increased abundance during muscle aging, which was independently verified by immunoblotting of differently aged human skeletal muscle samples. PMID: 22797148
5. The generation of CA III and IV autoantibodies, antioxidant enzymes, and cytokines might influence each other. PMID: 23049597
6. Crystallization and preliminary X-ray analysis of human carbonic anhydrase III PMID: 11976500
7. Data show that inserting histidine residues into the active site cavity of carbonic anhydrase II or III results in rates of proton transfer to the zinc-bound hydroxide that are antagonistic or suppressive with respect to the corresponding single mutants. PMID: 12171926
8. Proton transfer within the active-site cavity of carbonic anhydrase III PMID: 12484342
9. myoglobin/carbonic anhydrase III ratio in the blood proved to be a more specific indicator for myocardial damage than myoglobin alone after myocardial infarction. PMID: 12745799
10. CAIII expression is upregulated in kidney cortex samples from the end-stage kidney of a patient with Dent's disease owing to the G506E mutation of CLCN5 PMID: 18322545
11. CAIII promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway. PMID: 18444244
12. The level of CAIII is specifically insufficient in the skeletal muscle of myasthenia gravis patients. PMID: 19301202
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亞細胞定位：

Cytoplasm.
蛋白家族：

Alpha-carbonic anhydrase family
組織特異性：

Muscle specific.
數據庫鏈接：

HGNC: 1374

OMIM: 114750

KEGG: hsa:761

STRING: 9606.ENSP00000285381

UniGene: Hs.82129

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