C1D Antibody

中文名稱：

C1D兔多克隆抗體
貨號：

CSB-PA03474A0Rb
規格：

￥440
圖片：
Western Blot
Positive WB detected in: Hela whole cell lysate
All lanes: C1D antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 17 kDa
Observed band size: 17 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA03474A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA03474A0Rb at dilution of 1:100

Immunofluorescence staining of Hela cells with CSB-PA03474A0Rb at 1:533, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) C1D Polyclonal antibody
Uniprot No.：

Q13901
基因名：

C1D
別名：

1110036E10Rik antibody; AI875855 antibody; C1D antibody; C1D DNA binding protein antibody; C1D_HUMAN antibody; hC1D antibody; LRP1 antibody; MGC12261 antibody; MGC14659 antibody; MGC188504 antibody; Nuclear DNA binding protein antibody; Nuclear nucleic acid binding protein C1D antibody; Nuclear nucleic acid-binding protein C1D antibody; rCG23324 antibody; RGD1560600 antibody; Small unique nuclear receptor corepressor antibody; SUNCOR antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Nuclear nucleic acid-binding protein C1D protein (1-135AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，C1D Antibody (CSB-PA03474A0Rb)，的標記方式是Non-conjugated。對于C1D Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA03474B0Rb	C1D Antibody, HRP conjugated	ELISA
FITC	CSB-PA03474C0Rb	C1D Antibody, FITC conjugated
Biotin	CSB-PA03474D0Rb	C1D Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:2000-1:10000
IHC	1:50-1:500
IF	1:500-1:1000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.
基因功能參考文獻：
1. C1D is associated with the DNA repair complex and may promote repair of ultraviolet irradiation-induced DNA damage. PMID: 20530579
2. Results are consistent with a role for the exosome-associated protein C1D in the recruitment of the exosome to pre-rRNA to mediate the 3' end processing of the 5.8S rRNA. PMID: 17412707
3. Anti-C1D autoantibodies were observed in patients with polymyositis-scleroderma overlap syndrome. PMID: 17599775
4. TRAX enhances the DNA binding capacity of Translin, that binds to recombination regions in some malignancies. C1D interacts with TRAX following g-irradiation and prevents formation of TRAX/Translin complex, thereby inhibits any unwanted recombination. PMID: 11801738
5. The C1D protein interacts with the catalytic subunit of DNA-PK and is a very effective substrate for DNA-PK in vitro. Moreover, C1D directs the activation of DNA-PK in a manner that does not require DNA termini, suggesting a role for C1D in DNA repair. PMID: 9679063
顯示更多

收起更多
亞細胞定位：

Nucleus. Cytoplasm. Nucleus, nucleolus.
蛋白家族：

C1D family
組織特異性：

Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung an
數據庫鏈接：

HGNC: 29911

OMIM: 606997

KEGG: hsa:10438

STRING: 9606.ENSP00000348107

UniGene: Hs.602900

Most popular with customers

YWHAG Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
YWHAB Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF, FC

Species Reactivity: Human, Mouse, Rat
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XPNPEP1 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
XDH Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WFDC2 Recombinant Monoclonal Antibody

Applications: ELISA, WB, FC

Species Reactivity: Human