BTN3A2 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) BTN3A2 Polyclonal antibody
Uniprot No.：

P78410
基因名：

BTN3A2
別名：

BT3.2 antibody; BT3.3 antibody; BT3A2_HUMAN antibody; BTF4 antibody; BTN3A 2 antibody; BTN3A2 antibody; Butyrophilin protein antibody; Butyrophilin subfamily 3 member A2 antibody; Butyrophilin; subfamily 3; member A2 antibody; CD277 antibody; FLJ40011 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
基因功能參考文獻：
1. CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. PMID: 28447857
2. BTN3A2 genetic variants have role in gastric carcinogenesis. PMID: 28246015
3. BTN3A2 rs9104 was strongly associated with genotype 1 hepatitis C infection. PMID: 25928882
4. Three SNPs in BTN3A2 were associated with schizophrenia, rs12214031, rs9393709 and rs12199613. There was no interaction between these SNPs and HSV-1, CMV or toxoplasma exposure. PMID: 22966150
5. Results suggest that BT3.2 butyrophilin expression by epithelial cells may modulates the intratumoral infiltration of immune cells. PMID: 22685580
6. our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I Deabetes. PMID: 19295542
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亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Immunoglobulin superfamily, BTN/MOG family
組織特異性：

Detected in T-cells and natural killer cells.
數據庫鏈接：

HGNC: 1139

OMIM: 613594

KEGG: hsa:11118

STRING: 9606.ENSP00000348751

UniGene: Hs.376046

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