BTBD10 Antibody
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中文名稱：BTBD10兔多克隆抗體
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貨號(hào)：CSB-PA002841GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：BTBD10
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別名：BTBD10 antibody; GMRP1BTB/POZ domain-containing protein 10 antibody; Glucose metabolism-related protein 1 antibody
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human BTBD10
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells.
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基因功能參考文獻(xiàn)：
- findings suggest that reduced BTBD10 expression is closely linked to the pathogenesis of sporadic amyotrophic lateral sclerosis PMID: 23320755
- Collectively, these results suggest that the reduced expression of BTBD10 leads to motor neuron death both in vitro and in vivo. PMID: 22388351
- GMRP1 regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway. PMID: 21267538
- BTBD10 appears to behave as a suppressor of cell death including neuronal cell death related to amyotrophic lateral sclerosis and an enhancer of cell growth via its positive regulation of Akt phosphorylation. PMID: 18160256
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亞細(xì)胞定位：Nucleus. Cytoplasm.
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組織特異性：Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma.
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數(shù)據(jù)庫(kù)鏈接：
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