B3GNT5 Antibody

中文名稱：

B3GNT5兔多克隆抗體
貨號：

CSB-PA002503EA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA002503EA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA002503EA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) B3GNT5 Polyclonal antibody
Uniprot No.：

Q9BYG0
基因名：

B3GNT5
別名：

B3GNT5Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase antibody; EC 2.4.1.206 antibody; Lactotriaosylceramide synthase antibody; Lc(3)Cer synthase antibody; Lc3 synthase antibody; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 antibody; BGnT-5 antibody; Beta-1,3-Gn-T5 antibody; Beta-1,3-N-acetylglucosaminyltransferase 5 antibody; Beta3Gn-T5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein (65-344AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，B3GNT5 Antibody (CSB-PA002503EA01HU)，的標記方式是Non-conjugated。對于B3GNT5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA002503EB01HU	B3GNT5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA002503EC01HU	B3GNT5 Antibody, FITC conjugated
Biotin	CSB-PA002503ED01HU	B3GNT5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
基因功能參考文獻：
1. bone marrow samples of acute myeloid leukemia patients had 16-fold higher expression of B3GNT5 than those of healthy donors PMID: 22411838
2. Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x PMID: 18483624
亞細胞定位：

Golgi apparatus membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyltransferase 31 family
組織特異性：

Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus.
數據庫鏈接：

HGNC: 15684

OMIM: 615333

KEGG: hsa:84002

STRING: 9606.ENSP00000316173

UniGene: Hs.718506

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