AVIL Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) AVIL Polyclonal antibody
Uniprot No.：

O75366
基因名：

AVIL
別名：

Actin binding protein DOC 6 antibody; Actin binding protein DOC6 antibody; Advil antibody; Advillin antibody; AVIL antibody; AVIL_HUMAN antibody; DOC 6 antibody; DOC6 antibody; p92 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Advillin protein (623-819AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，AVIL Antibody (CSB-PA002464LA01HU)，的標記方式是Non-conjugated。對于AVIL Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA002464LB01HU	AVIL Antibody, HRP conjugated	ELISA
FITC	CSB-PA002464LC01HU	AVIL Antibody, FITC conjugated
Biotin	CSB-PA002464LD01HU	AVIL Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly.
基因功能參考文獻：
1. NMR structure of the C-terminal headpiece subdomains of advillin. Evaluation of F-actin-binding requirements. PMID: 15096633
2. Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. PMID: 18022635
亞細胞定位：

Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell junction, focal adhesion. Cell projection, neuron projection. Cell projection, axon.
蛋白家族：

Villin/gelsolin family
組織特異性：

Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. Expressed in podocytes (at protein level).
數據庫鏈接：

HGNC: 14188

OMIM: 613397

KEGG: hsa:10677

STRING: 9606.ENSP00000257861

UniGene: Hs.584854

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