ATP6V1H Antibody
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中文名稱：ATP6V1H兔多克隆抗體
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貨號：CSB-PA004431
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規格：￥1090
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圖片：
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Western Blot analysis of COLO205 cells using V-ATPase H Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：Atp6v1h antibody; ATPase; H+ transporting; lysosomal 50/57kDa; V1 subunit H antibody; CGI 11 antibody; CGI11 antibody; EC 3.6.3.14 antibody; MSTP042 antibody; NBP1 antibody; Nef binding protein 1 antibody; Nef-binding protein 1 antibody; Protein VMA13 homolog antibody; SFD antibody; SFDalpha antibody; SFDbeta antibody; V ATPase subunit H antibody; V-ATPase 50/57 kDa subunits antibody; V-ATPase subunit H antibody; V-type proton ATPase subunit H antibody; Vacuolar ATP synthase subunit H antibody; Vacuolar proton pump subunit H antibody; Vacuolar proton pump subunit SFD antibody; VATH_HUMAN antibody; VMA13 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the Internal region of Human V-ATPase H.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.
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基因功能參考文獻：
- These data provide evidence that partial loss of ATP6V1H function results in osteoporosis/osteopenia. PMID: 27924156
- These studies have uncovered a new, ATP6V1H-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9/MMP13 could be therapeutic targets for patients with this rare genetic disease. PMID: 28158191
- ATP6V1H may represent a critical molecular mechanism involved in the development of type 2 diabetes and its compilations through its important regulatory effect on vacuolar-ATPase activity. PMID: 21871445
- Our study shows that multiple mechanisms of pump dysfunction result from B1 subunit mutations with a common outcome being defective assembly PMID: 18368028
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蛋白家族：V-ATPase H subunit family
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組織特異性：Widely expressed.
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數據庫鏈接：
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