ATP5O Antibody
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中文名稱：ATP5O兔多克隆抗體
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貨號：CSB-PA002379ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA002379ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ATP5O Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：ATP synthase O subunit mitochondrial precursor antibody; ATP synthase subunit O antibody; ATP synthase; H+ transporting; mitochondrial F1 complex; O subunit antibody; ATP5O antibody; ATPO antibody; ATPO_HUMAN antibody; mitochondrial antibody; Mitochondrial ATP synthase; O subunit antibody; Oligomycin sensitivity conferral protein antibody; OSCP antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human ATP synthase subunit O, mitochondrial protein (24-213AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
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基因功能參考文獻：
- Upon IF1 interaction with the ATP synthase both the synthetic and hydrolytic activities of the engine of oxidative phosphorylation are inhibited. (Review) PMID: 26876430
- Sirt3 physically interacted with the OSCP and led to its subsequent deacetylation. PMID: 23046812
- Human mitochondrial F(1)F(0) ATP synthase was isolated with a one-step immunological approach. PMID: 12110673
- Genetic variation and age are associated with skeletal muscle ATP5O mRNA expression and glucose disposal rate, suggesting that combinations of genetic and non-genetic factors may cause the reduced expression of ATP5O in type 2 diabetes muscle PMID: 19274082
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亞細胞定位：Mitochondrion. Mitochondrion inner membrane.
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蛋白家族：ATPase delta chain family
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數據庫鏈接：
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