ATG101 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ATG101 Polyclonal antibody
Uniprot No.：

Q9BSB4
基因名：

ATG101
別名：

ATG101 antibody; Atg13-interacting protein antibody; ATGA1_HUMAN antibody; Autophagy-related protein 101 antibody; C12orf44 antibody; Chromosome 12 open reading frame 44 antibody; FLJ11773 antibody; OTTHUMP00000241687 antibody; OTTHUMP00000241688 antibody; OTTHUMP00000241689 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Autophagy-related protein 101 protein (1-218AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
基因功能參考文獻：
1. Structure of the human Atg13-Atg101 HORMA heterodimer in the ULK1 complex that controls autophagy has been described. PMID: 26299944
2. Data indicate mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis. PMID: 23640897
3. The identification of the novel protein, Atg101, and the validation of Atg13 and Atg101 as ULK1-interacting proteins, suggests an Atg1 complex is involved in the induction of macroautophagy in mammalian cells. PMID: 19287211
4. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
亞細胞定位：

Cytoplasm. Preautophagosomal structure.
蛋白家族：

ATG101 family
數據庫鏈接：

HGNC: 25679

OMIM: 615089

KEGG: hsa:60673

STRING: 9606.ENSP00000338990

UniGene: Hs.9911

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