ASGR2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ASGR2 Polyclonal antibody
Uniprot No.：

P07307
基因名：

ASGR2
別名：

ASGR2; CLEC4H2; Asialoglycoprotein receptor 2; ASGP-R 2; ASGPR 2; C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Asialoglycoprotein receptor 2 protein (63-286AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
基因功能參考文獻：
1. sH2a has the potential to be a uniquely sensitive and specific novel marker for liver fibrosis and function. PMID: 22096539
2. trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid PMID: 12089159
亞細胞定位：

Membrane; Single-pass type II membrane protein.
組織特異性：

Expressed exclusively in hepatic parenchymal cells.
數據庫鏈接：

HGNC: 743

OMIM: 108361

KEGG: hsa:433

STRING: 9606.ENSP00000347140

UniGene: Hs.654440

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