ARSE Antibody

中文名稱：

ARSE兔多克隆抗體
貨號：

CSB-PA002146LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA002146LA01HU diluted at 1:400 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA002146LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ARSE Polyclonal antibody
Uniprot No.：

P51690
基因名：

ARSE
別名：

ARSL antibody; ARSE antibody; Arylsulfatase L antibody; EC 3.1.6.- antibody; Arylsulfatase E antibody; ASE antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Arylsulfatase E protein (352-494AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ARSE Antibody (CSB-PA002146LA01HU)，的標記方式是Non-conjugated。對于ARSE Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA002146LB01HU	ARSE Antibody, HRP conjugated	ELISA
FITC	CSB-PA002146LC01HU	ARSE Antibody, FITC conjugated
Biotin	CSB-PA002146LD01HU	ARSE Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Exhibits arylsulfatase activity towards the artifical substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
基因功能參考文獻：
1. Data indicate that the neonatal detection test sensitivity obtained was 95% with a positive predictive value of 1 in the analyses for both the arylsulfatase E (ARSE) and melanoma antigen family H1 (MAGEH1) genes. PMID: 25366798
2. Results show that Around 40 perdcent of male patients with brachytelephalangic chondrodysplasia punctata do not have detectable ARSE mutations or known maternal etiological factors. PMID: 23470839
3. Clinical and molecular analysis of ARSE in CDPX1 patients supports heterogeneity for CDPX1-like phenotypes and sorting these out will help to define the biological pathway and genetic contributors. [ARSE] PMID: 18348268
相關疾病：

Chondrodysplasia punctata 1, X-linked recessive (CDPX1)
亞細胞定位：

Golgi apparatus, Golgi stack.
蛋白家族：

Sulfatase family
組織特異性：

Expressed in the pancreas, liver and kidney.
數據庫鏈接：

HGNC: 719

OMIM: 300180

KEGG: hsa:415

STRING: 9606.ENSP00000370526

UniGene: Hs.386975

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