ARHGEF9 Antibody
-
中文名稱：ARHGEF9兔多克隆抗體
-
貨號：CSB-PA002057ESR1HU
-
規格：￥440
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) ARHGEF9 Polyclonal antibody
-
Uniprot No.：
-
基因名：ARHGEF9
-
別名：9630036L12Rik antibody; A230067K14 antibody; ARHG9_HUMAN antibody; Arhgef9 antibody; Cdc42 guanine nucleotide exchange factor (GEF) 9 antibody; Collybistin antibody; collybistin I antibody; EIEE8 antibody; HPEM 2 antibody; hPEM-2 collybistin antibody; KIAA0424 antibody; mKIAA0424 antibody; OTTHUMP00000023424 antibody; OTTHUMP00000023425 antibody; OTTHUMP00000023427 antibody; PEM 2 antibody; PEM 2 homolog antibody; PEM-2 homolog antibody; PEM2 antibody; Rac/Cdc42 guanine nucleotide exchange factor 9 antibody; Rho guanine nucleotide exchange factor 9 antibody; RP11 357C3.4 antibody; RP23 230K20.3 antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Rho guanine nucleotide exchange factor 9 protein (307-516AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
-
基因功能參考文獻：
- Autism spectrum disorder patient with the smallest inactivating deletion in the collybistin gene. PMID: 27238888
- Collybistin forms a complex with mTOR and eIF3 and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism. PMID: 25898924
- Impairment of the membrane lipid binding activity of Collybistin R290H and a consequent defect in inhibitory synapse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in humans. PMID: 25678704
- Data indicate that ARHGEF9 is likely to be responsible for syndromic X-linked mental retardation associated with epilepsy. PMID: 21633362
- These results reveal that G(s) and G(q) signalings regulate hPEM-2 functions through PKA and c-Src in Neuro-2a neuroblastoma cells, respectively. PMID: 22033413
- major regulator of GABAergic postsynaptic gephyrin clustering PMID: 21807943
- Here we identified residues critical for interaction with gephyrin in the linker region between the SH3 and the DH domains of collybistin. PMID: 11727829
- translocates gephyrin to submembrane microaggregates; collybistin mutation (G55A)is found in exon 2 of the ARHGEF9 gene in a patient with clinical symptoms of both hyperekplexia and epilepsy PMID: 15215304
- Results show that hPEM-2 is a target protein of Smurf1. PMID: 18208356
顯示更多
收起更多
-
相關疾病：Epileptic encephalopathy, early infantile, 8 (EIEE8)
-
亞細胞定位：Cytoplasm. Cell junction, synapse, postsynaptic density.
-
組織特異性：Detected in brain. Detected at low levels in heart.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
