APRT Antibody
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中文名稱：APRT兔多克隆抗體
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貨號：CSB-PA001954DSR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA001954DSR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) APRT Polyclonal antibody
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Uniprot No.：
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基因名：APRT
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別名：Adenine phosphoribosyltransferase antibody; AMP antibody; AMP diphosphorylase antibody; AMP pyrophosphorylase antibody; APRT antibody; APT_HUMAN antibody; DKFZp686D13177 antibody; MGC125856 antibody; MGC125857 antibody; MGC129961 antibody; Transphosphoribosidase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Adenine phosphoribosyltransferase protein (1-180AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
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基因功能參考文獻：
- A long TA repeat in the promoter region of IL28B was associated with spontaneous HCV clearance. PMID: 25735432
- A new mutation, p.Gln147X, in APRT gene, was found in a patient with adenine phosphoribosyltransferase deficiency. PMID: 24986359
- Case study of 2 year old Japanese boy with APRT deficiency. Genetic analysis showed compound heterozygote APRT*J and missense mutation L33P. APRT deficiency should be suspected in patients with radiolucent kidney stones and urinary 2,8-DHA crystals. PMID: 21635362
- kinetic, regulatory and thermostability properties of APRT from erythrocytes of HGPRT deficient patients PMID: 14674717
- determination of structure and examination of role of deficiency in DHA-urolithiasis PMID: 15196008
- two novel mutations, G133D and V84M, were found in the APRT gene in Japanese patients with APRT deficiency PMID: 15571218
- APRT assay in a sample of patient hemolysate showed no detectable activity of the enzyme (25.56+/-9.55 U/L red blood cells in control healthy subjects). PMID: 17126311
- Data indicates that the flexible loop structure adopts an open conformation before and after binding of both substrates adenine and phosphoribosyl pyrophosphate. PMID: 18399692
- The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP are reported. PMID: 19399589
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相關疾病：Adenine phosphoribosyltransferase deficiency (APRTD)
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亞細胞定位：Cytoplasm.
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蛋白家族：Purine/pyrimidine phosphoribosyltransferase family
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數據庫鏈接：
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