ANKRD28 Antibody
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中文名稱：ANKRD28兔多克隆抗體
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貨號：CSB-PA929390
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規格：￥1100
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圖片：
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: CSB-PA929390(ANKRD28 Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 hours
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其他：
產品詳情
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Uniprot No.：
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基因名：ANKRD28
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別名：ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human ANKRD28
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.
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基因功能參考文獻：
- findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28. PMID: 27026398
- hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation PMID: 25902538
- These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity. PMID: 16564677
- CaMKII and GSK3 mediate regulation of PITK. PMID: 17023142
- ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. PMID: 19118547
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亞細胞定位：Nucleus, nucleoplasm. Note=Seems to be excluded from nucleoli.
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數據庫鏈接：
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