ANAPC5 Antibody

中文名稱：

ANAPC5兔多克隆抗體
貨號：

CSB-PA05104A0Rb
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA05104A0Rb at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ANAPC5 Polyclonal antibody
Uniprot No.：

Q9UJX4
基因名：

ANAPC5
別名：

2510006G12Rik antibody; AA408751 antibody; AA536819 antibody; AA986414 antibody; ANAPC 5 antibody; ANAPC5 antibody; Anaphase promoting complex subunit 5 antibody; Anaphase-promoting complex subunit 5 antibody; Apc 5 antibody; APC5 antibody; APC5_HUMAN antibody; Cyclosome subunit 5 antibody; PDL 108 antibody; PDL108 antibody; Periodontal ligament fibroblast protein antibody; RMC1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Anaphase-promoting complex subunit 5 protein (2-232AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ANAPC5 Antibody (CSB-PA05104A0Rb)，的標記方式是Non-conjugated。對于ANAPC5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA05104B0Rb	ANAPC5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA05104C0Rb	ANAPC5 Antibody, FITC conjugated
Biotin	CSB-PA05104D0Rb	ANAPC5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
基因功能參考文獻：
1. coexpression of APC5 and Axin genes significantly downregulated Wnt signaling in human SW480 CRC cells and inhibited cell growth. PMID: 28731177
2. Results show that Apc5 binds the poly(A) binding protein (PABP), which directly binds the internal ribosome entry site (IRES) element of platelet-derived growth factor 2 mRNA. PMID: 15082755
3. APC5 and APC7 suppress E1A-mediated transformation in a CBP/p300-dependent manner, indicating that these components of the APC/C may be targeted during cellular transformation PMID: 16319895
亞細胞定位：

Nucleus. Cytoplasm, cytoskeleton, spindle.
蛋白家族：

APC5 family
數據庫鏈接：

HGNC: 15713

OMIM: 606948

KEGG: hsa:51433

STRING: 9606.ENSP00000261819

UniGene: Hs.7101

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