AKAP4 Antibody
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中文名稱：AKAP4兔多克隆抗體
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貨號：CSB-PA311022
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA311022(AKAP4 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA311022(AKAP4 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：AKAP4
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別名：A kinase (PRKA) anchor protein 4 antibody; A kinase anchor protein 4 antibody; A kinase anchor protein 82 kDa antibody; A-kinase anchor protein 4 antibody; A-kinase anchor protein 82 kDa antibody; AKAP 4 antibody; AKAP 82 antibody; AKAP-4 antibody; AKAP4 antibody; AKAP4_HUMAN antibody; AKAP82 antibody; FSC 1 antibody; FSC1 antibody; hAKAP 82 antibody; hAKAP82 antibody; HI antibody; Major sperm fibrous sheath protein antibody; p82 antibody; PRKA 4 antibody; PRKA4 antibody; Protein kinase A anchoring protein 4 antibody; Protein kinase A-anchoring protein 4 antibody; Testis specific gene HI antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Fusion protein of Human AKAP4
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
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基因功能參考文獻：
- High AKAP4 expression is associated with reduced sperm motility. PMID: 29581387
- A significant association was found between AKAP4 gene expression and metastasis (P-value: 0.045), expression of the CTAG1B (NY-ESO-1) gene was not observed in our cases. PMID: 29480665
- the physiological role of the negative crosstalk between the cAMP/PKA/AKAP4 and the PKC/ERK1/2 pathways is to regulate capacitation and acrosome reaction. PMID: 27901058
- AKAP4 role in the proliferation and metastasis of thyroid cancer.AKAP4 is highly expressed in thyroid cancer. PMID: 27983916
- AKAP4 appears to be a novel Colorectal cancer-associated antigen with a potential for developing as a new clinical therapeutic target PMID: 26590805
- AKAP4 is a highly accurate biomarker for the detection of early stage lung cancer. PMID: 26160834
- SP17/AKAP4/PTTG1 are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients. PMID: 25739119
- The putative role of AKAP4 in early tumorigenesis is implicated as a biomarker and immunotherapeutic target for cervical cancer. PMID: 23478221
- Ablation of AKAP4 protein caused significant inhibition in cellular proliferation, colony-forming ability, migration and invasion ability of tumor cells. PMID: 23764900
- data suggests that AKAP4 may be used as serum based diagnostic test for an early detection and diagnosis of breast cancer and may be a potential target for immunotherapeutic use PMID: 23451156
- We demonstrate the aberrant expression of AKAP-4 in prostate cancer, which will potentially be developed as a biomarker in prostate cancer. PMID: 21520158
- AKAP4 is a novel target for protein S-nitrosylation in spermatozoa. PMID: 17683036
- Role of AKAP4 in sperm motility is unclear, vut absent or weak AKAP4-labelling is associated with absent or weak sperm. motility. PMID: 17712481
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亞細胞定位：Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum.
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蛋白家族：AKAP110 family
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組織特異性：Testis specific; only expressed in round spermatids.
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數(shù)據(jù)庫鏈接：
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