ADGRB2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ADGRB2 Polyclonal antibody
Uniprot No.：

O60241
基因名：

ADGRB2
別名：

ADGRB2 antibody; BAI2Adhesion G protein-coupled receptor B2 antibody; Brain-specific angiogenesis inhibitor 2 antibody
宿主：

Rabbit
反應種屬：

Human, Rat
免疫原：

Recombinant Human Adhesion G protein-coupled receptor B2 protein (1371-1545AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ADGRB2 Antibody (CSB-PA523985LA01HU)，的標記方式是Non-conjugated。對于ADGRB2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA523985LB01HU	ADGRB2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA523985LC01HU	ADGRB2 Antibody, FITC conjugated
Biotin	CSB-PA523985LD01HU	ADGRB2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
基因功能參考文獻：
1. These studies provide new insights into the signaling capabilities of the adhesion GPCR BAI2/ADGRB2 and shed light on how an apparent gain-of-function mutation to the receptor's C-terminus may lead to human disease. PMID: 28891236
2. This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
3. BAI2 is a functional GPCR regulated by proteolytic processing and activates the NFAT pathway PMID: 20367554
4. involvement of BAI2 in the ischemia-induced brain angiogenesis PMID: 12218411
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
組織特異性：

Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
數據庫鏈接：

HGNC: 944

OMIM: 602683

KEGG: hsa:576

STRING: 9606.ENSP00000362762

UniGene: Hs.524138

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