ADAMTS17 Antibody
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中文名稱：ADAMTS17兔多克隆抗體
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貨號：CSB-PA485300
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA485300(ADAMTS17 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA485300(ADAMTS17 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: NIH/3T3 cells, Primary antibody: CSB-PA485300(ADAMTS17 Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 hour
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其他：
產品詳情
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Uniprot No.：
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基因名：ADAMTS17
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別名：A disintegrin and metalloproteinase with thrombospondin motifs 17 antibody; A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 17 antibody; ADAM metallopeptidase with thrombospondin type 1 motif; 17 antibody; ADAM-TS 17 antibody; ADAM-TS17 antibody; ADAMTS 17 antibody; ADAMTS-17 antibody; ADAMTS17 antibody; ATS17_HUMAN antibody; EC 3.4.24. antibody; FLJ16363 antibody; FLJ32769 antibody; OTTHUMP00000194818 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human ADAMTS17
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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基因功能參考文獻：
- Secretion of ADAMTS17 requires O-fucosylation. ADAMTS17 binds fibrillin-2 but not fibrillin-1 and does not cleave either. ADAMTS17 regulates fibrillin isoform composition of microfibrils in the eye. PMID: 28176809
- higher Adamts17 expression is found in several human cancer cell subtypes, especially in breast ductal carcinoma and there is an inverse correlation between higher Adamts17 expression and patients' survival. PMID: 24906090
- The mutation in the Weill-Marchesani syndrome (WMS)- gene ADAMTS17 also causes WMS in an Indian family. PMID: 24940034
- A mutation in WMS-like gene ADAMTS17 also causes WMS. PMID: 24940034
- Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition. PMID: 23661674
- Recessive ADAMTS17 mutations are a recurrent cause of isolated spherophakia with short stature. PMID: 22486325
- ADAMTS17 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
- Homozygous mutation in ADAMTS17 causes lenticular myopia, ectopia lentis, glaucoma, spheropakia, and short stature. PMID: 19836009
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相關疾病：Weill-Marchesani-like syndrome (WMSL)
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亞細胞定位：Secreted, extracellular space, extracellular matrix.
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組織特異性：Isoform 1 and isoform 2 are expressed at high levels in the lung, brain, whole eye and retina. Isoform 1 shows a weaker expression in the heart, kidney and skeletal muscle. Isoform 2 shows a weaker expression in the kidney, bone marrow and skeletal muscle
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數據庫鏈接：
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