ACADSB Antibody
-
中文名稱：ACADSB兔多克隆抗體
-
貨號：CSB-PA001128GA01HU
-
規(guī)格：￥3,900
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：ACADSB
-
別名：2 MEBCAD antibody; 2 methyl branched chain acyl CoA dehydrogenase antibody; 2 methylbutyryl CoA dehydrogenase antibody; 2 methylbutyryl coenzyme A dehydrogenase antibody; 2-MEBCAD antibody; 2-methyl branched chain acyl-CoA dehydrogenase antibody; 2-methylbutyryl-CoA dehydrogenase antibody; 2-methylbutyryl-coenzyme A dehydrogenase antibody; ACAD7 antibody; ACADSB antibody; ACDSB_HUMAN antibody; acyl CoA dehydrogenase; short/branched chain antibody; acyl Coenzyme A dehydrogenase short branched chain antibody; mitochondrial antibody; OTTHUMP00000020685 antibody; OTTHUMP00000046795 antibody; SBCAD antibody; Short/branched chain specific acyl-CoA dehydrogenase antibody; short/branched chain specific acyl-CoA dehydrogenase; mitochondrial antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Human ACADSB
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產(chǎn)品提供形式：Liquid
-
應用范圍：ELISA,WB,IHC
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
-
功能：Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug.
-
基因功能參考文獻：
- the c.1165 A>G mutation before knowing whether the optimal screening cut-off would minimize true positives or false negatives for SBCADD associated with this mutation. PMID: 23712021
- Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients PMID: 22277967
- These findings confirm that SBCAD deficiency can be identified through newborn screening by acylcarnitine analysis. PMID: 20547083
- Differences between the rat and human enzyme at positions 383, 222, and 220 alter substrate specificity without affecting substrate binding. PMID: 12855692
- Identification and characterization of an IVS3+3A>G mutation (c.303+3A>G) in the SBCAD gene, and provide evidence that this mutation is disease-causing. PMID: 16317551
- Results examine the mechanistic basis for dysfunction of the common variant short-chain acyl-CoA dehydrogenases and demonstrate that mutations can have a large impact on the redox properties of the enzyme. PMID: 16331963
- Results indicate that substrate redox activation occurs in short-chain acyl-CoA dehydrogenase leading to a large enzyme midpoint potential shift. PMID: 16331964
顯示更多
收起更多
-
相關疾病：Short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD)
-
亞細胞定位：Mitochondrion matrix.
-
蛋白家族：Acyl-CoA dehydrogenase family
-
組織特異性：Ubiquitously expressed.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
