ACADL Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P28330
基因名：

ACADL
別名：

ACAD4 antibody; ACADL antibody; ACADL_HUMAN antibody; Acyl Coenzyme A dehydrogenase long chain antibody; Acyl-CoA dehydrogenase long chain antibody; FLJ94052 antibody; LCAD antibody; Long chain acyl CoA dehydrogenase antibody; Long-chain specific acyl-CoA dehydrogenase; mitochondrial antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human ACADL
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Ammonium Sulfate Precipitation
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
基因功能參考文獻(xiàn)：
1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease PMID: 24591516
2. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. PMID: 24121500
3. LCAD is minimally expressed in human skeletal muscle and likely does not play a significant role in long-chain fatty acid oxidation. PMID: 20363655
相關(guān)疾病：

Acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD)
亞細(xì)胞定位：

Mitochondrion matrix.
蛋白家族：

Acyl-CoA dehydrogenase family
數(shù)據(jù)庫鏈接：

HGNC: 88

OMIM: 609576

KEGG: hsa:33

STRING: 9606.ENSP00000233710

UniGene: Hs.471277

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