WDR77 Monoclonal Antibody
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中文名稱：WDR77鼠單克隆抗體
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貨號：CSB-MA232183
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規格：￥2621
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其他：
產品詳情
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產品描述：本產品為針對WDR77靶點設計的高特異性單克隆抗體（CUSABIO貨號：CSB-MA232183），靶向調控基因表達的關鍵表觀遺傳因子WDR77（WD重復結構域蛋白77）。該蛋白作為PRMT5甲基轉移酶復合物的核心組分，參與調控組蛋白H4R3對稱性甲基化及多種RNA代謝過程，其異常表達與腫瘤發生、干細胞分化等病理生理過程密切相關。經嚴格驗證，該抗體在ELISA、Western Blot及免疫細胞化學（ICC）實驗中均表現出優異性能，可同時識別人、小鼠、大鼠物種的同源蛋白，適用于多物種模型下的蛋白互作研究、細胞定位分析及信號通路探索。作為表觀遺傳學研究的核心工具，該WDR77抗體廣泛應用于腫瘤分子機制研究、干細胞重編程實驗、DNA損傷修復相關課題，尤其在探索前列腺癌、肺癌等實體瘤中PRMT5/WDR77復合物的致癌機制時具有重要科研價值。產品采用高純度抗原免疫制備，經多批次質控確保批次間穩定性，為基因調控網絡和表觀遺傳修飾研究提供可靠保障。
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別名：2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77;
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宿主：Mouse
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反應種屬：Human,Mouse,Rat
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免疫原：Purified recombinant Human WDR77 protein fragments expressed in E.coli.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Monoclonal
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抗體亞型：IgG1
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純化方式：Affinity purified
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克隆號：7D5
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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應用范圍：ELISA,WB,ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 ICC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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