HK1 Monoclonal Antibody
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中文名稱：HK1鼠單克隆抗體
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貨號：CSB-MA145499
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規(guī)格：￥2621
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：CUSABIO貨號：CSB-MA145494 HK1單克隆抗體是針對己糖激酶1（Hexokinase 1）研發(fā)的高特異性科研工具，該靶點(diǎn)作為糖酵解通路的關(guān)鍵限速酶，催化葡萄糖轉(zhuǎn)化為葡萄糖-6-磷酸的起始反應(yīng)，在細(xì)胞能量代謝調(diào)控中發(fā)揮核心作用，其表達(dá)異常與神經(jīng)退行性疾病發(fā)生及腫瘤細(xì)胞Warburg效應(yīng)密切相關(guān)。本產(chǎn)品經(jīng)嚴(yán)格驗(yàn)證適用于人類、犬類、豬、小鼠及大鼠等多物種樣本檢測，可兼容酶聯(lián)免疫吸附（ELISA）、蛋白質(zhì)印跡（Western Blot）和免疫細(xì)胞化學(xué)（ICC）三大實(shí)驗(yàn)平臺，為研究者提供跨物種比較研究的實(shí)驗(yàn)便利。在神經(jīng)科學(xué)領(lǐng)域可用于阿爾茨海默病模型中線粒體能量代謝研究，腫瘤生物學(xué)中適用于探究癌細(xì)胞糖酵解重編程機(jī)制，代謝性疾病方向可支持胰島素抵抗相關(guān)通路分析。該單抗具有高親和力和低交叉反應(yīng)特性，能夠精準(zhǔn)識別不同組織來源的HK1蛋白，為開展能量代謝調(diào)控、疾病模型構(gòu)建及藥物靶點(diǎn)篩選等基礎(chǔ)研究提供可靠檢測工具。
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別名：HKI, HXK1, HK1-ta, HK1-tb, HK1-tc
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宿主：Mouse
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反應(yīng)種屬：Human,Dog,Pig,Mouse,Rat
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免疫原：Purified recombinant HumanHK1 protein fragments expressed in E.coli.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Monoclonal
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抗體亞型：IgG1
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純化方式：Affinity purified
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克隆號：1G5
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
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應(yīng)用范圍：ELISA,WB,ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 ICC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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