ACTC1/ACTA1/ACTG2 Monoclonal Antibody
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中文名稱：ACTC1/ACTA1/ACTG2鼠單克隆抗體
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貨號(hào)：CSB-MA830329
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規(guī)格：￥1320
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圖片：
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IHC image of CSB-MA830329 diluted at 1:100 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.
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產(chǎn)品詳情
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產(chǎn)品描述：CUSABIO貨號(hào)：CSB-MA830329單克隆抗體是針對(duì)ACTC1、ACTA1及ACTG2肌動(dòng)蛋白家族研發(fā)的科研級(jí)檢測(cè)試劑，可特異性識(shí)別人類樣本中三種重要細(xì)胞骨架蛋白。肌動(dòng)蛋白作為細(xì)胞骨架核心組分，不僅參與細(xì)胞形態(tài)維持和運(yùn)動(dòng)調(diào)控，其不同亞型（ACTC1主要分布于心肌、ACTA1在骨骼肌表達(dá)、ACTG2集中于平滑肌）的異常表達(dá)與肌肉疾病、腫瘤轉(zhuǎn)移及纖維化病變密切相關(guān)。本產(chǎn)品經(jīng)ELISA及免疫組化（IHC）雙重驗(yàn)證，具有高親和力與特異性，適用于肌肉組織病理分析、細(xì)胞骨架動(dòng)態(tài)研究及疾病模型構(gòu)建。在心血管疾病機(jī)制探索中，可用于心肌細(xì)胞收縮功能研究；在腫瘤科研領(lǐng)域支持轉(zhuǎn)移相關(guān)細(xì)胞運(yùn)動(dòng)性檢測(cè)；針對(duì)消化道疾病模型則能精準(zhǔn)定位平滑肌異常增生。該抗體為多靶點(diǎn)同步檢測(cè)提供高效解決方案，特別適合需要同時(shí)觀察多種肌動(dòng)蛋白亞型表達(dá)水平的復(fù)合型研究，助力科研人員深入解析細(xì)胞骨架重構(gòu)在病理生理過(guò)程中的分子機(jī)制，是基礎(chǔ)醫(yī)學(xué)和細(xì)胞生物學(xué)研究的理想工具。
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Uniprot No.：
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宿主：Mouse
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from human Actin, Muscle Specific
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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克隆號(hào)：25B6
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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