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Sheep Follicle Stimulating Hormone (FSH) ELISA kit

文獻引用 (3) 說明書下載

產品詳情

產品描述：

綿羊卵泡刺激素(FSH)酶聯免疫試劑盒（CSB-E13170Sh）為雙抗夾心法ELISA試劑盒，定量檢測樣本中的FSH含量。FSH即促卵泡生成素，是垂體前葉嗜堿性細胞分泌的糖蛋白激素。它在生殖系統中至關重要，參與調控卵泡發育和精子生成。研究機制主要圍繞其與受體結合，激活信號通路，調節生殖細胞的生長、分化等過程，對治療生殖相關疾病意義重大。該產品為生殖生物學研究提供可靠工具，可用于探究繁殖周期調控機制、評估動物繁殖力、監測內分泌功能異常等科研場景，同時支持畜牧業中優良種畜的選育研究。適用于需要高重復性數據的體外實驗研究。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

FSHBFollitropin subunit beta ELISA kit; Follicle-stimulating hormone beta subunit ELISA kit; FSH-B ELISA kit; FSH-beta ELISA kit; Follitropin beta chain ELISA kit
縮寫：

FSH
Uniprot No.：

P01227
種屬：

Ovis aries (Sheep)
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Signal Transduction
測定原理：

quantitative
測定方法：

Sandwich
精密度：
線性度：
回收率：
標準曲線：
數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

功能：

Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
基因功能參考文獻：
1. A novel GnRH response element between -750 bp and -232 bp of the ovine FSHB promoter. PMID: 23874399
2. Data suggest that dietary components (phytoestrogens here) down-regulate basal secretion/total FSH (CGA+FSHB) production yet up-regulate gonadotropin-releasing hormone agonist-induced luteinizing hormone (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
3. In ewes, infusion with genistein decreased the level FSH-beta in the adenohypophysis. PMID: 15531133
4. Activation of TAK1 (and probably p38-MAPK), but not Smad3, is necessary for triggering induction of oFSHbeta by activin. PMID: 16081641
5. Activin gathers Smads and Smad-associated proteins at the promoter region to regulate expression of the ovine FSHB and overall follitropin production. PMID: 17584958
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亞細胞定位：

Secreted.
蛋白家族：

Glycoprotein hormones subunit beta family
數據庫鏈接：

KEGG: oas:443387

UniGene: Oar.430